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Decreased BDNF, trkB-TK+ and GAD67 mRNA expression in the hippocampus of individuals with schizophrenia and mood disorders
In this model we assume that protein synthesis and degradation are in balance and that no amino acids are used for growth
Investigators use GSH to model cellular redox homeostasis, study Phase II detoxification pathways, and probe protein S-glutathionylation as a post-translational regulatory mechanism
So basically, when this balance cannot be obtained in excess of eumelanin, then one would appear a lot darker along with hyperpigment
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