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Description

They also improve blood sugar control, reduce blood pressure, and lower the risk of cardiovascular disease

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SGLT2 inhibitors were chosen as the comparator given they are guideline-recommended second-line glucose-lowering medication and share similar cardiovascular benefits with GLP-1RA, which helps reduce confounding by indication

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People microdosing GLP-1s do so for: Mitigating Side Effects: Standard doses of GLP-1 agonists can cause significant gastrointestinal side effects, including nausea, vomiting, diarrhea, and constipation (2)

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The peptide expiration guide provides broader context on how peptides degrade over time

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