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Glutathione-mediated redox regulation is determined not only by the ratio of its reduced (GSH) and oxidized (GSSG) forms but also by their absolute quantities in a cell

The microbial metabolite agmatine acts as an FXR agonist to promote polycystic ovary syndrome in female mice

Since the early 1990s researchers have been testing whether that same protective signalling does anything elsewhere: rodent and cell studies have looked at whether it prompts new blood vessels to grow into damaged tissue, since a fresh blood supply is what lets repair get started at all

The peptide may activate repair pathways while simultaneously suppressing abnormal proliferation through mechanisms researchers are still working to characterize