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Risks include hypoglycemia, insulin resistance, fluid retention, and potential mitogenic effects , especially with long-term use
Glucagon (GCG) has a powerful catabolic effect that stimulates lipolysis, reduces food intake, slows gastric emptying, and increases energy expenditure
Genomic analyses have revealed specific somatic mutations at codon 132 of the IDH1 gene in a higher proportion of secondary GBMs (85%) as compared to primary lesions (5%) (24)
Participants Twenty-five patients consented to be contacted by a member of the research team, of which 13 consented to take part in the study prior to initiation of the GLP-1 receptor agonist and completed baseline questionnaires
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