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Interstitial Cystitis, also known as Bladder Pain Syndrome (BPS), is a chronic condition characterized by pelvic pain, discomfort, and frequent urination
an early phase 1b study reported that co-administration was feasible and that each components pharmacokinetics were not meaningfully altered by the other, which motivated the phase 3 program [3]
Mutated GST sequences were subcloned into pET-15b, pET-24d, pGEX 4T-1, and pCMV-2B expression vectors, and the mutated constructs were confirmed by DNA sequencing
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