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This is especially relevant for people with type 2 diabetes using tirzepatide in addition to existing diabetes medications

The dynamic changes in mitochondrial fusion and fission control the morphology of mitochondria, exchange of contents, and maintain the normal function of mitochondria at physiological or pathological levels [58]

Detailed search strategies are available in Supplementary Table 1

Of these articles, one was an open-label study (Ali et al., 2020) that was considered to have a high risk of bias for the blinding of participants and personnel and a high risk of bias for the blinding of outcome assessment