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Once the sponge has soaked up a "mess" (a free radical), it becomes saturated and cannot clean up any more until it is wrung out

37 Pelvic exam is crucial, especially to evaluate for surface hyperesthesia or pelvic muscle tightness/tenderness

That observation became the foundation for one of the most extensively cited copper-peptide research lines in tissue-biology literature, and its the reason GHK-Cu is still classified in research today as an endogenous signaling peptide rather than a synthetic compound designed from scratch