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*Correspondence: Natalia Chyliska [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
The CYP2E1-induced oxidative stress increases the intracellular GSH level by increasing the activation of GCS through Nrf2 nuclear translocation [74, 75, 84, 17]
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Catalysing these reactions, glutathione can pick up unpaired electrons and safely dispose of them
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