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doi:10.1007/s00216-012-6468-7
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They did however comment in their New England Journal of Medicine article that the affinity of lixisenatide for the GLP-1 receptor was up to four times greater than that of human GLP-1and there have been neuroprotective actions shown in animal models of Alzheimers disease. Together, I suspect these were likely strong rationales driving their choice of the use of Lixisenatide
bioRxiv2025 April 15
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