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Also, AC undergoes extensive metabolism, including oxidation, glucuronidation, sulfation, and methyl conjugation, yielding a wide range of metabolites

Long-term steroids carry many potential risks, including bone fractures, effects on height and metabolism, and immunosupression

While both are sterile and suitable for medication dilution, there are several key differences to consider and understanding these distinctions helps ensure medications remain effective and risks are minimised

doi: 10.3389/fimmu.2025.1677612 Received 08 August 2025 Revised 06 December 2025 Accepted 15 December 2025 Published 09 January 2026 Volume 16 - 2025 Edited by Eileen Gentleman, Kings College London, United Kingdom Reviewed by Gabriel Arellano, Northwestern University, United States Senthil Kumaran Satyanarayanan, Hong Kong Institute of Innovation and Technology, Hong Kong SAR, China Updates Copyright 2026 Jackson, Porter and Oakes