Stefan Kabisch, Charit University Medicine Berlin, Germany Updates Copyright 2023 Musazadeh, Alinejad, Esfahani, Kavyani, Keramati, Roshanravan, Mosharkesh and Dehghan
285 When UA levels are increased, RAGE signaling becomes activated, that ultimately lead to endothelial dysfunction, is a key feature of various cardiovascular diseases
To boost the antioxidant effect opt for: Retinoid + Antioxidants (Glutathione, Vitamin C, Superoxide Dismutase, Silymarin, Bakuchiol) Powerful antioxidants like Superoxide Dismutase, Glutathione and Vitamin C are great during the day as they help protect the skin against environmental aggressors and UV Rays alongside sunscreen
Skin sensitivity: an emerging signal Skin burning and abnormal touch sensitivity (dysesthesia) appears as a dose-related, reversible signal in two case series and post-market surveillance. Trials did not pre-specify it, and the tirzepatide label does not list it