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Saxenda is FDA-approved for weight management in adults (and some adolescents) with a BMI 30 or 27 with a comorbid condition

It should be noted that physiologic GLP-1R agonism in the periphery mediates food intake reduction via vagal afferent signaling as rats with a surgical subdiaphragmatic vagal deafferentation (SDA) exhibit a more mild food intake suppression in response to acute administration of GLP-1 analogues than sham operated animals (80, 81)

For one researcher in Texas, that means turning to a surprising source for a potential treatment, the venom from the desert predator lizard known as the Gila monster

Losing weight and building new, healthier eating habits can be a struggle for many people