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Studies show that metformin acts by boosting the activity of AMPK, a master metabolic regulator that favors fat- and sugar-burning and prevents their accumulation
A number of recombinant strategies have been developed to synthesize bispecific antibodies (BsAbs), which include single chain variable fragment (scFv)-derived formats such as diabodies, tandem diabodies, BiTEs (bispecific T-cell engager), and DARTs (Dual Affinity Re-Targeting), as well as immunoglo-bulin G (IgG)-based formats such as Triomab, DVD-Ig (Dual Variable Domain antibodies), and two-in-one antibodies 14
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Hosseini B, Nourmohamadi M, Hajipour S, et al
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