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Efficacy of statins in familial hypercholesterolaemia: a long term cohort study

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Ultimately, Pfizer discontinued the entire program in April 2025, citing that the risk-benefit profile, including a potential case of drug-induced liver injury (DILI) in a recent study, did not support further development

Oxidative stress also induces the stabilization of HIF-1, enhancing angiogenesis and metastasis [101]