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The most extensively documented involves upregulation of vascular endothelial growth factor (VEGF) and its receptor VEGFR2, promoting angiogenesis, the formation of new blood vessels, in injured tissue
Whilst we did not find this replicated in our meta-analysis in this particular brain region (nor in any of the individual studies included), nonetheless we did find this difference in the occipital region
And a great example of this is, I looked at a meta analysis of the risk of smoking on the risk of adenocarcinoma
investigators considered them unrelated, but no long-term oncology safety data exists)
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