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In this regard, the mitochondria-targeted SOD mimetic Mito-tempo has been shown to protect against APAP hepatotoxicity, while Tempo, which exhibits SOD activity but without its specific mitochondrial targeting, failed to protect against APAP-induced liver injury ( - generation in APAP hepatotoxicity
Carter BZ, Mak PY, Mak DH, Konopleva M, Cortes J, Andreeff M
The dual roles of red blood cells in tissue oxygen delivery: oxygen carriers and regulators of local blood flow
& Maibach, H
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