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Patience and adherence to the dosing schedule are essential for the best outcomes

Clinically, in patients with renal failure, acute kidney injury, dialysis and other pathological states of renal function deterioration, renal reabsorption function is impaired, resulting in a significantly lower serum free carnitine concentration than that in healthy people [255], and the metabolic profile of acylcarnitine also changes significantly [256]

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These candidates demonstrate clinical differentiation and innovation, moving beyond traditional biosimilar or fast-follower strategies