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Several compounds target overlapping or complementary pathways in ways that warrant consideration
Kennedy is actively working on human trials for this.
Advances in Enzymology and Related Areas of Molecular Biology
Indeed, there may be synergy between FGF-21 and GCG receptor agonism, due to their similar metabolic actions, particularly related to brown adipose tissue differentiation and activation [32], with FGF21 having additional actions in the liver, reducing hepatic lipogenesis and enhancing hepatic insulin sensitivity [66, 67]
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