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Diabetes-related thrombotic risk factors include: Hyperglycaemia-induced endothelial dysfunction , promoting a prothrombotic state Increased platelet reactivity and aggregation Elevated levels of clotting factors including fibrinogen and von Willebrand factor Chronic inflammation with raised inflammatory markers Impaired fibrinolysis , reducing the body's ability to break down clots Obesity independently increases thrombotic risk through multiple mechanisms

During colonoscopy preparation, this mechanism can interact with bowel-cleansing solutions in ways that require provider coordination to ensure adequate preparation quality

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