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Cold-like symptoms, including fever and loss of appetite, might also appear
The term impaired sensitivity to B12 more aptly captures this condition than functional B12 deficiency, encompassing a broader portrayal of the potential underlying pathological physiological process involving decreased responsiveness to B12 treatment, including B12 absorption, transport, intracellular metabolism, and mitochondrial MMA metabolism
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Whether metabolic benefits (improved insulin sensitivity, reduced visceral fat) persist, partially reverse, or fully reverse is unknown
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