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Pruritic skin disorders that lead to scratching and/or rubbing will usually develop more pigmentation than will nonpruritic conditions
4 , eaat3386 (2018)
In addition to release of PRR ligands, hepatocyte stress and death are associated with release of pro-inflammatory cytokines, including inflammasome-mediated interleukin-1 (IL-1), which further contributes to NASH-associated hepatitis (171)
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