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Ethacraplatin a dual-threat platinum (IV) prodrug is a cisplatin molecule coordinated to two ethacrynic acid ligands which is able to inhibit irreversibly GSTP1-1 enzymatic activity being reduced and cleaved as a consequence of binding (Fig

[18] LanCL1 has been identified as a binding and functional mediator of LAT8881 activity in neuropathic-pain models, but its role in adipocyte or whole-body metabolic effects remains unresolved