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People who have recently been hospitalized due to heart failure should be monitored closely if they are prescribed this medication since it can further worsen their condition in some cases
Hydrolysis: Peptide bonds degrade in aqueous conditions, producing inactive fragments
Similar substrate preferences and catalytic efficiencies are observed for SARS-CoV-2 and SARS-CoV PL pro , suggesting that inhibitors of SARS-CoV PL pro are a good starting point for lead compound optimization against SARS-CoV-2
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