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Peripheral neuropathy in diabetic patients on metformin is often due to two factors: diabetes itself and B12 deficiency

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This product is not a pharmaceutical and must not be used in humans or animals

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In the nervous system, Ca 2+ release into the cytosol through the mPTP activates neurotransmitter release by triggering vesicle exocytosis [186, 187]

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Others prefer to keep B12 as a more steady part of their wellness routine

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