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Gill SS et al
Derived from a compound found in the French lilac (goats rue), Metformin is now the most widely used oral medication for managing type 2 diabetes globally, often prescribed off-label for conditions like polycystic ovary syndrome (PCOS) and, in some cases, for weight loss
As such, some results were felt to be inaccurate with patients on GLP-1 RA therapy for very short durations being seen to continue to lose weight after cessation
Setting attainable goals can prevent disappointment and encourage persistence, even when progress seems slow
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