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Anti-aging Effects By promoting the release of growth hormone, scientists suggest that Ipamorelin may help counteract some of the effects of aging by supporting collagen production, skin elasticity, and overall tissue regeneration

This triple-action mechanism sets it apart from earlier weight loss peptides like semaglutide (GLP-1 only) or tirzepatide (GLP-1 and GIP), making it one of the most potent metabolic compounds studied to date

These include individuals with a personal or family history of medullary thyroid carcinoma, those with Multiple Endocrine Neoplasia syndrome type 2, and anyone with known hypersensitivity to semaglutide or product components

In April 2026, retatrutide crossed 28.7% matching bariatric surgery