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The Medicines and Healthcare products Regulatory Agency (MHRA) has warned healthcare professionals to be aware of the potential risk of pulmonary aspiration in patients using glucagon-like peptide-1 (GLP-1) or dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists (GLP-1 RAs), who undergo surgery or procedures with general anaesthesia or deep sedation

Formulation and Branding While Semaglutide is the active ingredient, Ozempic is one of its brand names

Epub 2011 Apr 8

The medication's effect on gastric emptying can exacerbate pre-existing gastroesophageal reflux disease (GERD), potentially causing retrosternal burning or pressure that mimics cardiac symptoms