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Consider Other Nutrient Deficiencies Low B12 levels can sometimes be linked to deficiencies in other essential nutrients, such as iron and folate
It is likely that the larger number of statistically significant changes to the microbiome observed in the groups switched from WD to LD reflects their more numerous exposures to different diets, longitudinal changes in dietary exposure, the stress associated with diet switch, the negative energy state achieved by treatment and/or diet-driven weight loss, or a combination of these factors, but it may also be related to differences in terminal body weight and fat mass since both adiposity and diet composition have been shown to modulate the mouse gut microbiome profile
Lipo B12 shots can help
Your prescribing provider gives written reconstitution and dosing instructions specific to your vial size and prescribed dose
