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For detailed instructions on how to administer your dose, please speak with your healthcare provider

Extended interruptions may warrant restarting at a lower dose to minimize gastrointestinal side effects, particularly if the patient had previously experienced significant nausea or vomiting during dose escalation

Other side effects, like thyroid problems, gallstones, or pancreatitis, and even a rare form of blindness, are far less common, but often necessitate discontinuation

Immunostaining of brain tissue for Iba1 and GFAP revealed that microglia and astrocytes were markedly activated in GCLC-KO mouse brains (Fig