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The shortage has prompted the FDA to allow companies to manufacture generic semaglutide formulas as stated on the FDA website: When a drug is in shortage, compounders may be able to prepare a compounded version of that drug if they meet certain requirements in the Federal Food, Drug, and Cosmetic (FD&C) Act
The drug is available in both injectable form and as an oral tablet, making it more convenient and versatile for different patient need Semaglutide's potency stems from its structural similarity to the human GLP-1 hormone but with significant modifications that make it resistant to degradation by the enzyme dipeptidyl peptidase-4 (DPP-4)
doi:10.1001/jama.2018.3024
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