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Investigators shared new data on retatrutide, an investigational, once-weekly injectable glucose-dependent insulinotropic polypeptide (GIP)/glucagon-like peptide-1 (GLP-1)/glucagon (GCG) receptor agonist, and its effects on obesity, type 2 diabetes, and nonalcoholic steatohepatitis (NASH)

doi: 10.1083/jcb.201708007 83 KlaunigJEWangZPuXZhouS

This is supported by cell-killing assays which indicate increased lysis of NK cell-sensitive lines after GLP-1 treatment, alongside heightened production of IFN- and granzyme B [173]