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Most side effects are mild and involve digestive issues such as nausea, constipation, diarrhea, abdominal pain, bloating, gas, heartburn, headache, fatigue, dizziness, runny nose and sore throat

These effects were coupled to an amelioration in lipid metabolism and hepatic steatosis, which markedly exceeded the effect of single GLP-1RA treatment (72)

The most reliable non-laboratory indicator of degradation is reduced effectiveness

This study demonstrated significant improvements in parameters such as HbA1c, body weight, and lipid profiles, along with a reduced need for rescue medications to control hyperglycemia ( Among the prospective studies on this pharmacological combination, real-world evidence also plays a significant role