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The recommended dosages are based on the data from clinical trials for that specific use. For both types, higher doses may lead to negative side effects Increasing the dosage for both types of medications can come with negative side effects (nausea, vomiting, constipation, fatigue, loss of appetite and more)

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In the UK, Adam Taylor, professor of anatomy at Lancaster University, has been watching cases like this closely, as the scientific community continues to raise the alarm on this market which operates in a legal and regulatory middle zone