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176 The second phase of the nervous tissue response is cell proliferation, and this is manifested by proliferation of fibroblasts and pericytes, which form extracellular matrix to produce the fibrotic scar 177,178 that rapidly replaces lost neural parenchyma

These reductions appear early in treatment and are sustained, likely driven by the combination of weight loss, improved insulin sensitivity, and reduced systemic inflammation

Because of this, Vitamin B12 is an important nutrient when considering athletics and appropriate weight loss and body composition programs

Most clinical guidelines recommend baseline labs and periodic monitoring