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Despite minimal effects on Vt (actual volume of air taken in each breath), GSHee did elicit a sustained increase in both PIF and PEF, which suggests the thiolester either directly affected the force of contraction of skeletal muscle in the extrinsic (inspiratory) and intrinsic (expiratory) intercostals and/or diaphragm
Am J Physiol Gastrointest Liver Physiol 2007
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