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Besides the well-known targets such as the inhibition of the mTOR signaling pathway, several additional metformin and phenformin targets (e.g., mGPDH, ATF3, STAT3, GSK3, cyclins) have been identified in other cancers (Thakur et al., 2019)
Farias JG, Puebla M, Acevedo A, et al
It is not a quick fix for minor weight loss but a clinical tool for significant health improvement
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