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Food and Drug Administration (FDA) draft guidance, key opinion leader (KOL) discussions and company checks reinforce our belief that there is an opportunity for these agents to become a new therapeutic tool for treating obesity
Glutathione peroxidase 4 (GPX4), recently best known as the key regulator of ferroptosis implicated in many diseases, including OA, actually has long been identified and reportedly possesses multiple significant biological functions
Female predominance in AE reports (65.3% vs 30.5% male) persists despite global diabetes prevalence favoring males 39 , suggesting either biological susceptibility or heightened health-seeking behavior in women
