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2019;8(12):e012356
: Strong adoption driven by clinical efficacy and patient convenience Single-dose formats leading due to ease of administration Diabetes remains the dominant indication, with added cardiovascular and renal benefits North America continues to lead, supported by innovation, investment, and early adoption : A GLP-1 receptor agonist delivering proven glycemic control and ~15% weight reduction
These include different GLP-1/GIP combinations with varying receptor affinity profiles, triple agonists that add glucagon activity, and oral formulations of dual agonists
Similarly, Zepbound and Mounjaro share the same active ingredient, tirzepatide
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