sinha et al. eur j clin nutr 2018 liposomal glutathione A Targeted Metabolomic Assessment of Oral Bioavailability and Safety in Humans: A Randomized Crossover Clinical Trial sinha et al. liposomal glutathione

Some of these adverse effects reported were Toxic Epidermal Necrolysis (a rare but life-threatening skin condition characterized by painful blisters and large areas of skin peeling), air embolism, thyroid dysfunction, and liver, kidney, and neurologic toxicity (The dark side of skin lightening- PubMed) With the proliferation of med-spas in an unregulated fashion, there is a risk of inadequately trained or untrained people giving IV injections in a non-sterile way, which can lead to sepsis and transmission of infections like HIV and hepatitis

Improper use of Glutathione may lead to skin problems, including irritation

doi:10.1038/s41467-020-20790-0 7

Mendelian randomization: can genetic epidemiology contribute to understanding environmental determinants of disease