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Healthcare providers will evaluate individual patient needs, considering medical history, current health status, and specific weight management goals before prescribing appropriate protocols

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Red asterisks indicate significance of GLP-1RA/Tesaglitazar over Vhcl, blue asterisks indicate significance of Tesaglitazar over Vhcl

Since overall, DPP-4 inhibitors could not provide cardioprotection in clinical trials, 40 it can currently not be excluded that simultaneous stabilization of other DPP-4 substrates (eg, substance P or fibrin 41,42 ) may interfere with GLP-1(7-36) mediated antiplatelet effects of DPP-4 inhibitors in patients, thus requiring further investigation