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In the fish, creatine plus phosphocreatine concentrations in skeletal muscle were 1315, 1316, and 112125 times those in the proximal intestine, kidneys, and liver, respectively, whereas GSH concentrations in the liver were 3.23.5, 5.36.6, and 911 times those in the proximal intestine, kidneys, and skeletal muscle, respectively

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While the effects of GIP receptor antagonism on these outcomes remain unknow, GIPR knockout mice have been shown to exhibit impaired learning and memory, as well as reduced synaptic plasticity (111)