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doi: 10.1001/jamapsychiatry.2024.4789
The pituitary responds as if the body is producing GH naturally, which means the downstream IGF-1 response and tissue effects follow normal biological patterns
When monoglutamate folates are taken up into cells, particularly in the liver and kidney where they can be stored (but also in other cells), they are polyglutamated through the action of the enzyme folylpolyglutamate synthase
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