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The actual B12 remains in your system longer, but active levels gradually decline as your body utilises it
The difference between clinical and practical dosing Clinical trials operated under controlled conditions that do not reflect real-world use
[5] [6] Early-phase clinical trials including a Phase 2 trial published in the New England Journal of Medicine (2023) have reported significant reductions in body weight and improvements in metabolic markers, though this evidence remains preliminary and is not sufficient to establish a clinical dosing or reconstitution standard
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