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*Nutrients*, 11(10), 2412
In pancreatic cancer cells, oncogenic K-Ras maintains the nucleotide pool via the MAPK-dependent signaling pathway, leading to MYC upregulation, and the use of MEK inhibitors reduces the incorporation of glutamine-derived nitrogen into purine nucleotides 38
in the absence of normal gut microbiota in the mouse dams, the expression of BEC claudin-5 and occludin is diminished and an increase in BBB permeability is observed in the offspring (Welcome, 2019)
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