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Figure from Rossing et al NDT 2023 Primary Outcome This was a composite of time of first occurrence of: Onset of kidney failure (persistent eGFR 28 days or initiation of long-term KRT, kidney transplantation) Persistent 50% reduction in eGFR from baseline Death from kidney or CV causes Secondary Outcomes Confirmatory secondary outcomes were analyzed hierarchically

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(2007) J Inherit Metab Dis

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In addition, fasting levels of glucose were unchanged both in F rats compared to C rats (F rats = 123 5 mg/dL

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