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Such bidirectional interaction between hyperandrogenism and insulin resistance/hyperinsulinemia likely plays a key role in the pathogenesis of PCOS 12,13,14 , since elevated testosterone promotes obesity and insulin resistance/hyperinsulinemia by altering body composition and insulin signaling in skeletal muscle and adipose tissue, while hyperinsulinemia contributes to increase androgen levels via ovarian-dependent mechanisms 5
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Application: Spray evenly over the face on cleansed skin or over makeup
However, it is important to consult with your healthcare provider before taking any additional medications to ensure they do not interact with semaglutide or other treatments you are using
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