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This benefit is particularly relevant if youre regularly exposed to pollution, alcohol, stress, and poor sleep, all of which can increase oxidative stress and place additional demands on the liver
(Science!) Because of this, theres actually no tolerable upper intake level (UL) for B12 (the max dose you can take before you experience side effects)
However, it is recognized that antioxidant mechanisms, such as the Nrf2/Keap1 pathway, superoxide dismutases (SODs), catalase, and glutathione peroxidases, play a crucial role in modulating oxidative stress and LPO levels, thereby indirectly influencing oncogenic signalling [134]
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