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Skin Rash: There can be a mild rash, which is usually self-limiting

Specifically, HF reduces cardiac output, directly decreasing blood flow to peripheral tissues and organs, leading to intestinal ischemia

Nat Prod Res 38:31733181

Many studies have examined the effects of riboflavin on various diseases such as cataract ( Reference Cumming, Mitchell and Smith 7 ) , night blindness ( Reference Graham, Haskell and Pandey 8 ) , some cancers (oesophageal, cervical and colorectal) ( Reference Siassi and Ghadirian 9 Reference de Vogel, Dindore and van Engeland 11 ) , anaemia ( Reference Powers, Hill and Mushtaq 12 ) and CVD ( Reference Powers 13 )