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First, it involved a patient who already had neuropathy, raising the question of whether pre-existing nerve damage creates vulnerability to GLP-1-associated allodynia

Potential additional beneficial effects of these drugs on bone are depicted GLP-1 GLP-1 plays a key role in maintaining glucose homeostasis by enhancing glucose-dependent insulin secretion from pancreatic beta-cells, 7 as well as inhibiting glucagon secretion and suppressing appetite