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Oral versus intramuscular administration of vitamin B12 for the treatment of patients with vitamin B12 deficiency: a pragmatic, randomised, multicentre, non-inferiority clinical trial undertaken in the primary healthcare setting (Project OB12)

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Preventing and Treating Deficiency Vitamin B-12 injections are commonly used to prevent or treat pernicious anemia and B-12 deficiency

For broader questions about how safe these medications are in general, the SELECT trial data, and what the 2024 to 2026 evidence shows on the most-discussed concerns, see our separate guide on whether weight-loss injections are safe